The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F01%3A23010304" target="_blank" >RIV/68378050:_____/01:23010304 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation.

Original language description

Several of the CD98 antibodies induced homotypic aggregation of U937 cells without affecting cellular viability or growth. Some CD29 antibodies partially inhibited CD98-induced aggregation. Some CD98 antibodies were potent inhibitors of CD29-induced aggregation. Two antibodies to CD147 were also potent inhibitors of both the aggregation and the protein tyrosine phosphorylation induced via CD98 ligation. The results support a role for CD98 within a multimolecular unit that regulates cell aggregation.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/GA310%2F99%2F0349" target="_blank" >GA310/99/0349: Low-affinity monoclonal antibodies as specific tolls targeting functionally important subsets of leukocyte surface receptors</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Blood

ISSN

0006-4971

e-ISSN

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Volume of the periodical

98

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

374-382

UT code for WoS article

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EID of the result in the Scopus database

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