Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering rafts lipid composition.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F01%3A23010415" target="_blank" >RIV/68378050:_____/01:23010415 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering rafts lipid composition.

Original language description

Treatment of Jurkat T cells with polyunsaturated eicosapentaenoic acid results in marked enrichment of polyunsaturated fatty acids (PUFA) in lipids from isolated rafts. Palmitate-labeled kinase Lck and LAT were both displaced from lipid rafts indicatingthat acylation by PUFAs is not required for protein displacement from rafts in PUFA-treated T cells. These data indicate that displacement of acylated proteins from rafts PUFA-treated T cells is predominantly due to altered raft lipid composition.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/GA310%2F99%2F0349" target="_blank" >GA310/99/0349: Low-affinity monoclonal antibodies as specific tolls targeting functionally important subsets of leukocyte surface receptors</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Biological Chemistry

ISSN

0021-9258

e-ISSN

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Volume of the periodical

276

Issue of the periodical within the volume

40

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

37335-37340

UT code for WoS article

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EID of the result in the Scopus database

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