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The c-src1 gene visualized by in situ hybridization on Xenopus laevis chromosomes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F03%3A00109716" target="_blank" >RIV/68378050:_____/03:00109716 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The c-src1 gene visualized by in situ hybridization on Xenopus laevis chromosomes

  • Original language description

    Fluorescent in situ hybridization (FISH) followed by tyramide signal amplification was used to map the site of the c-src1 gene on Xenopus laevis chromosomes. Positive results were obtained with a cDNA probe of about 1 kb. The c-src1 gene is located in the subcentromeric region in the long arm of one of the acrocentric chromosomes of the G category (classification according to Graf and Kobel, 1991). This is the first time that it was possible to map a single copy gene by FISH on X. laevis chromosomes. The c-src1 gene and the Xenopus major histocompatibility complex (MHC) 1b locus, which consists of 20 tandemly arranged gene copies, are situated on different chromosomes of the G category

  • Czech name

    Gen c-src1 vizualizovaný hybridizací in situ na chromozomech Xenopus laevis

  • Czech description

    Fluorescenční hybridizace in situ (FISH) s následnou amplifikací tyramidového signálu byla využita k mapování umístění genu c-src1 na chromozomech Xenopus laevis. Byly získány pozitivní výsledky se sondou cDNA o velikosti cca 1 kb. Gen c-src1 se nacházív subcentromerické oblasti na dlouhém rameni jednoho z akrocentrických chromozomů kategorie G (klasifikace podle Grafa a Kobela, 1991). Je to poprvé, co se podařilo mapovat gen o jediné kopii pomocí FISH na chromozomech X. laevis. Gen c-src1 a lokus 1b hlavního histokompatibilitního komplexu (MHC) X. laevis, který je složen z 20 po sobě následujících kopií genu, se nacházeji na odlišných chromozomech kategorie G

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cytogenetic and Genome Research

  • ISSN

  • e-ISSN

  • Volume of the periodical

    103

  • Issue of the periodical within the volume

    -

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    4

  • Pages from-to

    169-172

  • UT code for WoS article

  • EID of the result in the Scopus database