Preparation, production and labelling of scFv against TU-20 and HIV.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F03%3A23033041" target="_blank" >RIV/68378050:_____/03:23033041 - isvavai.cz</a>

Alternative codes found

RIV/46356088:_____/03:00000005

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Preparation, production and labelling of scFv against TU-20 and HIV.

Original language description

Monoclonal antibody (mAb) TU 20 against beta-III neurotubulin, a specific component of neural cytoskeleton, is useful for labelling with radioactive nuclides and consequent detection of local levels of neurotubulin or its fragments in patients' tissues.Findings of increased local levels may indicate certain neurodegenerative diseases or an acute damage of neural cells. This work describes production of a recombinant single-chain form (scFv) of mAb TU20, the procedures for its labelling with iodine radionuclides, and assessment of stability and antigen-binding properties of the radiolabelled product in ELISA tests.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cancer Biotherapy & Radiopharmacenticals

ISSN

1084-9785

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

1

Pages from-to

285

UT code for WoS article

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EID of the result in the Scopus database

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