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Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F07%3A00091554" target="_blank" >RIV/68378050:_____/07:00091554 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells

  • Original language description

    We determined the expression, distribution and interaction of beta-III and gamma-tubulins in astrocytic gliomas and T98G glioblastoma cell line. In contrast with astrocytes, on T98G cells we found striking amount of gamma-tubulin in soluble cytoplasmic pool. Whereas both tubulins formed complexes in cytoplasm, beta-III did not associate with insoluble gamma-tubulin aggregates.

  • Czech name

    BetaIII-tubulin a gama-tubulin jsou koexprimovány a formují komplexy v lidských glioblastomech

  • Czech description

    Byla porovnána distribuce, exprese a interakce beta-III a gama-tubulinu u astrocytů a lidské glioblastomové linie T98G. U T98G buněk byla pozorována vysoká exprese gama-tubulinu v cytoplazmě, kde vytváří komplexy s beta-III-tubulinem. Toto atypické chování obou proteinů odráží proces transformace gliových buněk.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LC545" target="_blank" >LC545: Functional Organisation of the Cell</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neurochemical Research

  • ISSN

    0364-3190

  • e-ISSN

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

    1387-1398

  • UT code for WoS article

  • EID of the result in the Scopus database