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The spectrum of cytokeratins expressed in the adult human cornea, limbus and perilimbal conjunctiva

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F11%3A00357702" target="_blank" >RIV/68378050:_____/11:00357702 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/11:9840 RIV/00064165:_____/11:9840

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The spectrum of cytokeratins expressed in the adult human cornea, limbus and perilimbal conjunctiva

  • Original language description

    The most intense staining present throughout the cornea was observed for CK3, CK5 and CK14; CK19 was found at the corneal periphery only. CK4 and CK10/13 revealed mild to moderate positivity mostly in the superficial layers of the cornea. The suprabasalcell layers of all examined areas showed a strong positivity for CK16. A heterogeneous staining pattern with a centrifugal decrease in the signal was observed for CK8 and CK18. CK5/6, CK14 and CK19 were present in the limbus, where a positive signal forCK3 was observed in the suprabasal and superficial cells only. In contrast to the cornea, CK15 appeared in the basal and suprabasal layers of the limbus. The perilimbal conjunctiva showed strong immunostaining for CK10/13, CK14 and CK19. A moderate signal for CK7 was detected in the superficial layers of the conjunctiva. qRT-PCR confirmed CK6 and CK18 expression in the corneal and conjunctival epithelium.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Histology and Histopathology

  • ISSN

    0213-3911

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    ES - SPAIN

  • Number of pages

    9

  • Pages from-to

  • UT code for WoS article

    000285921200005

  • EID of the result in the Scopus database