Targeting genes in living mammals by RNA interference
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F11%3A00371760" target="_blank" >RIV/68378050:_____/11:00371760 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/bfgp/elr013" target="_blank" >http://dx.doi.org/10.1093/bfgp/elr013</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/bfgp/elr013" target="_blank" >10.1093/bfgp/elr013</a>
Alternative languages
Result language
angličtina
Original language name
Targeting genes in living mammals by RNA interference
Original language description
More than a decade has passed since the discovery of RNA interference (RNAi), an eukaryotic sequence-specific degradation of mRNA induced by complementary double-stranded RNA (dsRNA). RNAi became a common tool for controlled down-regulation of gene expression in cultured cells, as well as in various model organisms. This review summarizes RNAi-based tools for silencing genes in living mammals, which include: (i) transgenic RNAi strategies, where RNAi is triggered by a transgene transmitted through the germline and (ii) approaches, where an RNAi trigger is delivered into an adult animal.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Briefings in Functional Genomics
ISSN
2041-2649
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
238-247
UT code for WoS article
000293301300009
EID of the result in the Scopus database
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