Long and small noncoding RNAs during oocyte-to-embryo transition in mammals

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F17%3A00487078" target="_blank" >RIV/68378050:_____/17:00487078 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1042/BST20170033" target="_blank" >http://dx.doi.org/10.1042/BST20170033</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1042/BST20170033" target="_blank" >10.1042/BST20170033</a>

Result language

angličtina

Original language name

Long and small noncoding RNAs during oocyte-to-embryo transition in mammals

Original language description

Oocyte-to-embryo transition is a process during which an oocyte ovulates, is fertilized, and becomes a developing embryo. It involves the first major genome reprogramming event in life of an organism where gene expression, which gave rise to a differentiated oocyte, is remodeled in order to establish totipotency in blastomeres of an early embryo. This remodeling involves replacement of maternal RNAs with zygotic RNAs through maternal RNA degradation and zygotic genome activation. This review is focused on expression and function of long noncoding RNAs (lncRNAs) and small RNAs during oocyte-to-embryo transition in mammals. LncRNAs are an assorted rapidly evolving collection of RNAs, which have no apparent protein-coding capacity. Their biogenesis is similar to mRNAs including transcriptional control and post-transcriptional processing. Diverse molecular and biological roles were assigned to lncRNAs although most of them probably did not acquire a detectable biological role. Since some lncRNAs serve as precursors for small noncoding regulatory RNAs in RNA silencing pathways, both types of noncoding RNA are reviewed together.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10604 - Reproductive biology (medical aspects to be 3)

Project

<a href="/en/project/LO1419" target="_blank" >LO1419: Biomodels for Health - Center for model organisms</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biochemical Society Transactions

ISSN

0300-5127

e-ISSN

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Volume of the periodical

45

Issue of the periodical within the volume

říjen

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

1117-1124

UT code for WoS article

000418092200008

EID of the result in the Scopus database

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