MDSCs in infectious diseases: regulation, roles, and readjustment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00505122" target="_blank" >RIV/68378050:_____/19:00505122 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s00262-018-2277-y" target="_blank" >https://link.springer.com/article/10.1007/s00262-018-2277-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00262-018-2277-y" target="_blank" >10.1007/s00262-018-2277-y</a>

Result language
angličtina
Original language name
MDSCs in infectious diseases: regulation, roles, and readjustment
Original language description
Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence supported by functional assays on the roles of different subsets of MDSCs in acute and chronic infections, including pathogen-associated malignancies, and discusses strategies to modulate MDSC dynamics to benefit the host.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30102 - Immunology

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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