Efficient generation of transgenic animal models using in vivo electroporation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523242" target="_blank" >RIV/68378050:_____/19:00523242 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Efficient generation of transgenic animal models using in vivo electroporation
Original language description
The generation of animal model systems to study protein function or to mimic human genetic diseases is a valuable tool in biomedical research. Using traditional methods for the model generation requires expensive equipment and is time consuming. Recently, the CRISPR/Cas technology not only improved the efficiency of genomic manipulations, it also opened up new ways for the delivery of the reagents to the cells. In this book chapter we describe the iGONAD method allowing targeted mouse model production applicable for a wide range of research labs to introduce the desired genomic modifications without the need of special equipment.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Advances in Disease Models
ISBN
978-80-88011-06-4
Number of pages of the result
8
Pages from-to
226-233
Number of pages of the book
310
Publisher name
OPTIO CZ
Place of publication
Praha
UT code for WoS chapter
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