Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F21%3A00544578" target="_blank" >RIV/68378050:_____/21:00544578 - isvavai.cz</a>
Result on the web
<a href="https://www.journal-of-hepatology.eu/article/S0168-8278(20)33664-3/fulltext" target="_blank" >https://www.journal-of-hepatology.eu/article/S0168-8278(20)33664-3/fulltext</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jhep.2020.09.021" target="_blank" >10.1016/j.jhep.2020.09.021</a>

Result language
angličtina
Original language name
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice
Original language description
Background & Aims: Interleukin (IL)-6 cytokine family members contribute to inflammatory and regenerative processes. Engagement of the signaling receptor subunit gp130 is common to almost all members of the family. In the liver, all major cell types respond to IL-6-type cytokines, making it difficult to delineate cell type-specific effects. We therefore generated mouse models for liver cell type-specific analysis of IL-6 signaling.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10601 - Cell biology

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)