Variation in mouse chemical signals is genetically controlled and environmentally modulated
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F23%3A00573981" target="_blank" >RIV/68378050:_____/23:00573981 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/23:00573981 RIV/00216208:11310/23:10469145
Result on the web
<a href="https://www.nature.com/articles/s41598-023-35450-8" target="_blank" >https://www.nature.com/articles/s41598-023-35450-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-023-35450-8" target="_blank" >10.1038/s41598-023-35450-8</a>
Alternative languages
Result language
angličtina
Original language name
Variation in mouse chemical signals is genetically controlled and environmentally modulated
Original language description
In most mammals and particularly in mice, chemical communication relies on the detection of ethologically relevant fitness-related cues from other individuals. In mice, urine is the primary source of these signals, so we employed proteomics and metabolomics to identify key components of chemical signalling. We show that there is a correspondence between urinary volatiles and proteins in the representation of genetic background, sex and environment in two house mouse subspecies Mus musculus musculus and M. m. domesticus. We found that environment has a strong influence upon proteomic and metabolomic variation and that volatile mixtures better represent males while females have surprisingly more sex-biased proteins. Using machine learning and combined-omics techniques, we identified mixtures of metabolites and proteins that are associated with biological features.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
13
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
8573
UT code for WoS article
001001070500060
EID of the result in the Scopus database
2-s2.0-85160268236