Envisioning a role for nuclear actin in prophase I spermatocytes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F23%3A00580243" target="_blank" >RIV/68378050:_____/23:00580243 - isvavai.cz</a>
Result on the web
<a href="https://www.frontiersin.org/articles/10.3389/fcell.2023.1295452/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fcell.2023.1295452/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fcell.2023.1295452" target="_blank" >10.3389/fcell.2023.1295452</a>
Alternative languages
Result language
angličtina
Original language name
Envisioning a role for nuclear actin in prophase I spermatocytes
Original language description
Actin is a multi-functional protein that is involved in numerous cellular processes including cytoskeleton regulation, cell migration, and cellular integrity. In these processes, actin's role in respect to its structure, complex mechanical, and protein-binding properties has been studied primarily in the cytoplasmic and cellular membrane compartments. However, its role in somatic cell nuclei has recently become evident where it participates in transcription, chromatin remodeling, and DNA damage repair. What remains enigmatic is the involvement of nuclear actin in physiological processes that lead to the generation of germ cells, in general, and primary spermatocytes, in particular. Here, we will discuss the possible role and nuclear localization of actin during meiotic prophase I and its interaction with chromatin remodeling complexes, the latter being essential for the control of pairing of homologous chromosomes, cross-over formation, and recombination. It is our hope that this perspective article will extend the scope of actin's nuclear function in germ cells undergoing meiotic division.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/GA23-06605S" target="_blank" >GA23-06605S: Interplay of cytoskeleton and membrane morphology during formation of immunological synapse</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Cell and Developmental Biology
ISSN
2296-634X
e-ISSN
2296-634X
Volume of the periodical
11
Issue of the periodical within the volume
Nov
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
1295452
UT code for WoS article
001116674400001
EID of the result in the Scopus database
2-s2.0-85178885451