Semi-Automated MicroCT Analysis of Bone Anatomy and Mineralization in Mouse Models
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F24%3A00617300" target="_blank" >RIV/68378050:_____/24:00617300 - isvavai.cz</a>
Result on the web
<a href="https://currentprotocols.onlinelibrary.wiley.com/doi/epdf/10.1002/cpz1.980" target="_blank" >https://currentprotocols.onlinelibrary.wiley.com/doi/epdf/10.1002/cpz1.980</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cpz1.980" target="_blank" >10.1002/cpz1.980</a>
Alternative languages
Result language
angličtina
Original language name
Semi-Automated MicroCT Analysis of Bone Anatomy and Mineralization in Mouse Models
Original language description
The skeletal system mirrors several processes in the vertebrate body that impact developmental malfunctions, hormonal disbalance, malfunction of calcium metabolism and turn over, and inflammation processes such as arthrosis. X-ray micro computed tomography is a useful tool for 3D in situ evaluation of the skeletal system in a time-related manner, but results depend highly on resolution. Here, we provide the methodological background for a graduated evaluation from whole-body analysis of skeletal morphology and mineralization to high-resolution analysis of femoral and vertebral microstructure. We combine an expert-based evaluation with a machine-learning-based computational approach, including pre-setup analytical task lists. © 2024 Wiley Periodicals LLC. Basic Protocol 1: In vivo microCT scanning and skeletal analysis in mice. Basic Protocol 2: Ex vivo high-resolution microCT scanning and microstructural analysis of the femur and L4 vertebra.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Protocols
ISSN
2691-1299
e-ISSN
2691-1299
Volume of the periodical
4
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
22
Pages from-to
e980
UT code for WoS article
001253165200001
EID of the result in the Scopus database
2-s2.0-85185826434