High-field gradient permanent micromagnets for targeted drug delivery with magnetic nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F10%3A00365807" target="_blank" >RIV/68378271:_____/10:00365807 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
High-field gradient permanent micromagnets for targeted drug delivery with magnetic nanoparticles
Original language description
We analytically investigate several micromagnetic systems aimed at the optimization of drug and gene delivery processes and show their applicability to the controlled positioning of magnetic nanoparticles. The systems considered are: i) a square array ofcylindrical microneedles, ii) a planar stepped array of magnets, and iii) a Halbach array of micromagnets. We calculate spatial distributions of force components acting on a magnetic nanoparticle and the field gradients produced by these magnetic configurations. These calculations show that array geometries tend to enhance the field gradients and forces that can be obtained from a given material. The benefits of the proposed micromagnetic systems?tunability, scalability, and ability of creation of magnetic flux distributions with high-gradient areas allowing precise focusing of magnetic nanoparticles (MNPs)?are also discussed.
Czech name
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Czech description
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Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers
ISBN
978-0-7354-0866-1
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
152-157
Publisher name
American institute of physics
Place of publication
Melville
Event location
Rostock
Event date
May 25, 2010
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000287170600022

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