Lensless coherent imaging of proteins and supramolecular assemblies: Efficient phase retrieval by the charge flippingalgorithm

Result code in IS VaVaI

RIV/68378271:_____/13:00398212 - isvavai.cz

Result on the web

http://dx.doi.org/10.1016/j.jsb.2013.01.008

DOI - Digital Object Identifier

10.1016/j.jsb.2013.01.008

Result language

angličtina

Original language name

Lensless coherent imaging of proteins and supramolecular assemblies: Efficient phase retrieval by the charge flippingalgorithm

Original language description

Diffractive imaging using the intense and coherent beam of X-ray free-electron lasers opens new perspectives for structural studies of single nanoparticles and biomolecules.Simulations were carried out to generate 3D oversampled diffraction patterns of non-crystalline biological samples,ranging from peptides and proteins to megadalton complex assemblies,and to recover their molecular structure from nanometer to near-atomic resolutions.Using these simulated data,we show here that iterative reconstructionmethods based on standard and variant forms of the charge flipping algorithm,can efficiently solve the phase retrieval problem and extract a unique and reliable molecular structure.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BM - Solid-state physics and magnetism

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Structural Biology

ISSN

1047-8477

e-ISSN

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Volume of the periodical

182

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

106-116

UT code for WoS article

000318391100006

EID of the result in the Scopus database

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