Regioselective Friedel-Crafts acylation of calix[4]arenes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F15%3A00451274" target="_blank" >RIV/68378271:_____/15:00451274 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.tet.2015.02.021" target="_blank" >http://dx.doi.org/10.1016/j.tet.2015.02.021</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tet.2015.02.021" target="_blank" >10.1016/j.tet.2015.02.021</a>

Result language
angličtina
Original language name
Regioselective Friedel-Crafts acylation of calix[4]arenes
Original language description
FriedeleCrafts acylation of 25,27-dialkoxycalix[4]arenes has been studied. Direct acylation of de-tertbutylated calixarene using acyl chlorides and AlCl3 in 1,2-dichloroethane provided the corresponding diacyl derivatives regioselectively in high yields.Furthermore, ipso-substitution in the tert-butylated series under the same reaction conditions is possible, albeit in lower yields. As indicated by the unsuccessful application of this chemistry to O-acyl derivatives, the ipso-acylation reaction of calix[4]arenes proceeds by direct attack at the upper rim and not by a Fries rearrangement mechanis m.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Project
<a href="/en/project/GA14-03276S" target="_blank" >GA14-03276S: Aspherical effects and their application for statistically correct crystal structure analysis</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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