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Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy

Result description

Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed [1-3]. Here, the B-11( p,alpha)2 alpha nuclear fusion reaction channel, where three alpha particles are produced with an average energy around 4MeV, is considered [4]. These alphas are able to penetrate the cells nucleus and strongly damage their DNA. In addition, gamma prompts emitted by the proton Boron nuclear reactions can be used for on-line proton beam imaging purposes.

Keywords

instrumentation for particle-beam therapytargetsspallation source targetsradioisotope productionneutrino and muon sources

The result's identifiers

Alternative languages

  • Result language

    angličtina

  • Original language name

    Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy

  • Original language description

    Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed [1-3]. Here, the B-11( p,alpha)2 alpha nuclear fusion reaction channel, where three alpha particles are produced with an average energy around 4MeV, is considered [4]. These alphas are able to penetrate the cells nucleus and strongly damage their DNA. In addition, gamma prompts emitted by the proton Boron nuclear reactions can be used for on-line proton beam imaging purposes.

  • Czech name

  • Czech description

Classification

  • Type

    Jimp - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10306 - Optics (including laser optics and quantum optics)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Instrumentation

  • ISSN

    1748-0221

  • e-ISSN

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    Mar

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    1-4

  • UT code for WoS article

    000406997400059

  • EID of the result in the Scopus database

    2-s2.0-85017478691

Basic information

Result type

Jimp - Article in a specialist periodical, which is included in the Web of Science database

Jimp

OECD FORD

Optics (including laser optics and quantum optics)

Year of implementation

2017