Influence of photoinduced isomerization on the chiral separation of novel liquid crystalline materials with a diazene moiety
Result description
The influence of photoinduced isomerization on the enantiomeric separation of two newly synthesized liquid crystalline materials (with one chiral center and one diazene moiety) was studied by high-performance liquid chromatography on a chiral stationary phase. There were separated into their E and Z isomeric forms. Under the optimized conditions, we were able to separate the S and R enantiomers of both materials in their E isomeric form. The chiral separation of LC 1 possessing a similar structure to LC 2 provided baseline separation in its Z isomeric form, but separation of LC 2 after UV irradiation was unsuccessful. We demonstrate that (1) much more complex compounds can also be successfully separated despite the bulkiness of the achiral part of the structure and (2) photoinduced isomerization even for such complex molecules still strongly influences their chromatographic properties.
Keywords
chiral separationdiazeneshigh-performance liquid chromatographyliquid-crystalline materialsphotoinduced isomerization
The result's identifiers
Result code in IS VaVaI
Alternative codes found
RIV/60461373:22340/18:43915513
Result on the web
DOI - Digital Object Identifier
Alternative languages
Result language
angličtina
Original language name
Influence of photoinduced isomerization on the chiral separation of novel liquid crystalline materials with a diazene moiety
Original language description
The influence of photoinduced isomerization on the enantiomeric separation of two newly synthesized liquid crystalline materials (with one chiral center and one diazene moiety) was studied by high-performance liquid chromatography on a chiral stationary phase. There were separated into their E and Z isomeric forms. Under the optimized conditions, we were able to separate the S and R enantiomers of both materials in their E isomeric form. The chiral separation of LC 1 possessing a similar structure to LC 2 provided baseline separation in its Z isomeric form, but separation of LC 2 after UV irradiation was unsuccessful. We demonstrate that (1) much more complex compounds can also be successfully separated despite the bulkiness of the achiral part of the structure and (2) photoinduced isomerization even for such complex molecules still strongly influences their chromatographic properties.
Czech name
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Czech description
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Classification
Type
Jimp - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
GA16-12150S: Self-assembling photosensitive materials with multiple functionality
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Separation Science
ISSN
1615-9306
e-ISSN
—
Volume of the periodical
41
Issue of the periodical within the volume
15
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
3034-3041
UT code for WoS article
000440842600003
EID of the result in the Scopus database
2-s2.0-85051221554
Result type
Jimp - Article in a specialist periodical, which is included in the Web of Science database
OECD FORD
Analytical chemistry
Year of implementation
2018