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Nanocrystalline diamond-based impedance sensors for real-time monitoring of adipose tissue-derived stem cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00504656" target="_blank" >RIV/68378271:_____/19:00504656 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/19:00504656 RIV/68407700:21110/19:00327328 RIV/68407700:21230/19:00327328 RIV/68407700:21460/19:00327328

  • Result on the web

    <a href="https://doi.org/10.1016/j.colsurfb.2019.01.048" target="_blank" >https://doi.org/10.1016/j.colsurfb.2019.01.048</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.colsurfb.2019.01.048" target="_blank" >10.1016/j.colsurfb.2019.01.048</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nanocrystalline diamond-based impedance sensors for real-time monitoring of adipose tissue-derived stem cells

  • Original language description

    Here we present a diamond-based impedance sensor with built-in gold IDT as a promising platform for simultaneous electrical and optical monitoring of adipose tissue-derived stem cells (ASCs). The impedance spectra were collected in a wide frequency from 100 Hz to 50 kHz for 90 h of cell cultivation. Absolute impedance spectra were analyzed in terms of cell properties monitored by a high-resolution digital camera. The sensors detected three phases of cell growth: the phase of cell attachment and spreading, the phase of cell proliferation, and the stationary phase without significant changes in cell number. These results were confirmed by simultaneous live cell imaging. The design of the sensing electrode is discussed, pointing out its enhanced sensitivity for a certain case. The diamond-based sensor appeared to be more sensitive for detecting the cell-substrate interaction in the first phase of cell growth, while the control system was more sensitive in the second phase of cell growth.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20201 - Electrical and electronic engineering

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Colloids and Surfaces B-Biointerfaces

  • ISSN

    0927-7765

  • e-ISSN

  • Volume of the periodical

    177

  • Issue of the periodical within the volume

    May

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    130-136

  • UT code for WoS article

    000468720700015

  • EID of the result in the Scopus database

    2-s2.0-85060851825