Determination of optical purity of lactic acid-based chiral liquid crystals and corresponding building blocks by chiral high-performance liquid chromatography and supercritical fluid chromatography

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00511153" target="_blank" >RIV/68378271:_____/19:00511153 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22310/19:43919055 RIV/60461373:22330/19:43919055 RIV/60461373:22810/19:43919055

Result on the web

<a href="http://hdl.handle.net/11104/0301482" target="_blank" >http://hdl.handle.net/11104/0301482</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules24061099" target="_blank" >10.3390/molecules24061099</a>

Result language

angličtina

Original language name

Determination of optical purity of lactic acid-based chiral liquid crystals and corresponding building blocks by chiral high-performance liquid chromatography and supercritical fluid chromatography

Original language description

In this study we aimed to verify synthetic methods of liquid crystals (LCs) recently published in the literature, which are used nowadays to prepare chiral building blocks based on lactic acid, for their enantioselectivity. We have focused on the development of an analytical chiral separation method for target liquid crystalline materials. Using a chiral polysaccharide-based column operated in liquid chromatography mode, we show that not all published methods of LC synthesis are enantioselective, which could lead to significant differences in the properties of the resulting materials. We show that high-performance liquid chromatography with UV detection and supercritical fluid chromatography with UV and mass spectrometry detection enable full control over the chemical and optical purity of the target LCs and the corresponding chiral building blocks.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GJ16-17689Y" target="_blank" >GJ16-17689Y: Novel chiral ion exchange-type stationary phases for enantiomer separation</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

1420-3049

e-ISSN

—

Volume of the periodical

24

Issue of the periodical within the volume

6

Country of publishing house

CH - SWITZERLAND

Number of pages

11

Pages from-to

1-11

UT code for WoS article

000465503800075

EID of the result in the Scopus database

2-s2.0-85063573780