A vesicle-to-sponge transition via the proliferation of membrane-linking pores in omega-3 polyunsaturated fatty acid-containing lipid assemblies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00520788" target="_blank" >RIV/68378271:_____/19:00520788 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.molliq.2019.01.124" target="_blank" >https://doi.org/10.1016/j.molliq.2019.01.124</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.molliq.2019.01.124" target="_blank" >10.1016/j.molliq.2019.01.124</a>

Result language
angličtina
Original language name
A vesicle-to-sponge transition via the proliferation of membrane-linking pores in omega-3 polyunsaturated fatty acid-containing lipid assemblies
Original language description
Nanostructure evolution and the membrane reorganization of diluted lipid dispersions of selfassembled monoolein (MO)/eicosapentaenoic acid (EPA, 20:5) mixtures by synchrotron small-angle X-ray scattering (SAXS) and cryogenic transmission electron microscopy (cryo-TEM) microscopy.At ambient temperature, the topological transition occurred through the proliferation ofmembrane-linking pores (MLP)within the individual lipid nanoparticles. The density of the MLP pores varied starting from the nanoparticle center toward the periphery. The generation of MLP is governed by the amphiphilic composition and leads to formation of 3D networks of aqueous channels inside the nanoparticles, i.e. spongosomes. It can be concluded that the incorporation of a ω-3 polyunsaturated fatty acid at increasing concentration causes swelling inhibition (dehydration) of the host liquid crystalline architectures.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10305 - Fluids and plasma physics (including surface physics)

Project
<a href="/en/project/LQ1606" target="_blank" >LQ1606: ELI Beamlines: International Center of Excelence</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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