Synthesis, characterisation and supercritical fluid chromatography enantioseparation of new liquid crystalline materials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00536056" target="_blank" >RIV/68378271:_____/20:00536056 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/20:10422442

Result on the web

<a href="https://doi.org/10.1080/02678292.2020.1733684" target="_blank" >https://doi.org/10.1080/02678292.2020.1733684</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02678292.2020.1733684" target="_blank" >10.1080/02678292.2020.1733684</a>

Result language

angličtina

Original language name

Synthesis, characterisation and supercritical fluid chromatography enantioseparation of new liquid crystalline materials

Original language description

Enantiomeric excess (EE) highly affects the mesomorphic properties of mesogens containing centre of chirality. Thus, there is need of methods for evaluation of the EE of newly synthesised compounds as it should be considered when discussing the mesomorphic properties. We report synthesis and characterisation of ten new racemic mixtures based on (R,S)-3-octanol, which were used to develop an enantioseparation method that can be used for the assessment of the EE of chiral liquid crystals and their mixtures. The mesomorphic properties of novel materials were measured. Supercritical fluid chromatography with polysaccharide-based chiral stationary phases was used to develop reliable method for enantioseparation of the materials. A complete separation of (S) and (R) enantiomers with resolution values higher than 2.0 was obtained for all materials using simple mobile phase. The enantiomer elution order was assessed using pure (S) enantiomers of all materials. For all materials (R) enantiomer elutes first which is advantageous for use as optical purity control of newly synthesised (S) enantiomers.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GA20-19655S" target="_blank" >GA20-19655S: Strategy for on-line protein digestion followed by separation in mixed-mode chromatography</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Liquid Crystals

ISSN

0267-8292

e-ISSN

—

Volume of the periodical

47

Issue of the periodical within the volume

12

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

1832-1843

UT code for WoS article

000527426800001

EID of the result in the Scopus database

2-s2.0-85082427490