Fast UHPLC enantioseparation of liquid crystalline materials with chiral center based on octanol in reversed-phase and polar organic mode
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00560618" target="_blank" >RIV/68378271:_____/20:00560618 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/20:10413777
Result on the web
<a href="https://doi.org/10.1007/s00706-020-02622-5" target="_blank" >https://doi.org/10.1007/s00706-020-02622-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00706-020-02622-5" target="_blank" >10.1007/s00706-020-02622-5</a>
Alternative languages
Result language
angličtina
Original language name
Fast UHPLC enantioseparation of liquid crystalline materials with chiral center based on octanol in reversed-phase and polar organic mode
Original language description
Fast baseline enantioseparation of twenty racemic liquid crystalline compounds was carried out via ultra-performance liquid chromatography through direct enantioseparation in polar organic and reversed-phase modes. Tris(3-chloro-5-methylphenylcarbamate) derivative of amylose was used as chiral stationary phase, the chiral selector was covalently mmobilized on sub-2 μm silica particles. Experiments were done using either pure acetonitrile as mobile phase or simple binary mobile phases consisting of acetonitrile/water mixtures. Studied materials are a set of structurally similar compounds comprising two different structures of chiral center, various length of alkoxy spacer and four patterns of lateral substitution of aromatic core by fluorine. The compounds do not contain any ionizable group. The effect of the enantiomer structure on the retention and enantioseparation was evaluated. Flow rate and column temperature were optimized as part of method development.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/EF16_019%2F0000760" target="_blank" >EF16_019/0000760: Solid State Physics for 21st century</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Monatshefte fur Chemie
ISSN
0026-9247
e-ISSN
1434-4475
Volume of the periodical
151
Issue of the periodical within the volume
8
Country of publishing house
AT - AUSTRIA
Number of pages
6
Pages from-to
1235-1240
UT code for WoS article
000555979300008
EID of the result in the Scopus database
2-s2.0-85085570057