Co-adjuvant nanoparticles for radiotherapy treatments of oncological diseases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F21%3A00545253" target="_blank" >RIV/68378271:_____/21:00545253 - isvavai.cz</a>
Result on the web
<a href="http://hdl.handle.net/11104/0322003" target="_blank" >http://hdl.handle.net/11104/0322003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/app11157073" target="_blank" >10.3390/app11157073</a>
Alternative languages
Result language
angličtina
Original language name
Co-adjuvant nanoparticles for radiotherapy treatments of oncological diseases
Original language description
In this review, we describe the most recent methods exploiting heavy nanoparticles and hybrid nanomaterials aiming at improving the traditional X-rays-based treatments. High-Z nanoparticles are proposed as radiosensitizers due to their ability to stop the ionizing radiation and to increase the locally delivered therapeutic dose. Other nanoparticles working as catalysts can generate reactive oxygen species upon X-rays exposure. Thanks to their high toxicity and reactivity, these species promote DNA cancer cells damage and apoptosis. Hybrid nanoparticles, composed by scintillators coupled to organic molecules, are suitable in X-rays activated photodynamic therapy. This work highlights the roles played by the diverse nanoparticles, upon ionizing radiation irradiation, according to their physico-chemical properties, surface functionalization, and targeting strategies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Sciences-Basel
ISSN
2076-3417
e-ISSN
2076-3417
Volume of the periodical
11
Issue of the periodical within the volume
15
Country of publishing house
CH - SWITZERLAND
Number of pages
27
Pages from-to
7073
UT code for WoS article
000682000100001
EID of the result in the Scopus database
2-s2.0-85111647560