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Strong structural and electronic binding of bovine serum albumin to ZnO via specific amino acid residues and zinc atoms

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00561891" target="_blank" >RIV/68378271:_____/22:00561891 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21230/22:00353786

  • Result on the web

    <a href="https://doi.org/10.1002/cphc.202100639" target="_blank" >https://doi.org/10.1002/cphc.202100639</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/cphc.202100639" target="_blank" >10.1002/cphc.202100639</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Strong structural and electronic binding of bovine serum albumin to ZnO via specific amino acid residues and zinc atoms

  • Original language description

    ZnO biointerfaces with serum albumin have attracted noticeable attention due to the increasing interest in developing ZnO-based materials for biomedical applications. ZnO surface morphology and chemistry are expected to play a critical role on the structural, optical, and electronic properties of albumin-ZnO complexes. Yet there are still large gaps in the understanding of these biological interfaces. Herein we comprehensively elucidate the interactions at such interfaces by using atomic force microscopy and nanoshaving experiments to determine roughness, thickness, and adhesion properties of BSA layers adsorbed on the most typical polar and non-polar ZnO single-crystal facets. These experiments are corroborated by force field (FF) and DFTB calculations on ZnO-BSA interfaces. We show that BSA adsorbs on all the studied ZnO surfaces while interactions of BSA with ZnO are found to be considerably affected by the atomic surface structure of ZnO.n

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10305 - Fluids and plasma physics (including surface physics)

Result continuities

  • Project

    <a href="/en/project/GC19-02858J" target="_blank" >GC19-02858J: Charge transfer and microbiological interactions of hybrid metal oxide nanostructures</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ChemPhysChem

  • ISSN

    1439-4235

  • e-ISSN

    1439-7641

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    25-33

  • UT code for WoS article

    000722264500001

  • EID of the result in the Scopus database

    2-s2.0-85119672612