Photochemistry of (Z)-isovinylneoxanthobilirubic acid methyl ester, a bilirubin dipyrrinone subunit: femtosecond transient absorption and stimulated Raman emission spectroscopy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00568051" target="_blank" >RIV/68378271:_____/22:00568051 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/22:10444111 RIV/60076658:12310/22:43904994 RIV/00216208:11110/22:10444111 RIV/00216224:14310/22:00126178
Result on the web
<a href="https://doi.org/10.1021/acs.joc.1c02870" target="_blank" >https://doi.org/10.1021/acs.joc.1c02870</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.joc.1c02870" target="_blank" >10.1021/acs.joc.1c02870</a>
Alternative languages
Result language
angličtina
Original language name
Photochemistry of (Z)-isovinylneoxanthobilirubic acid methyl ester, a bilirubin dipyrrinone subunit: femtosecond transient absorption and stimulated Raman emission spectroscopy
Original language description
Bilirubin (BR) is an essential metabolite formed by the catabolism of heme. Phototherapy with blue-green light can be applied to reduce high concentrations of BR in blood and is used especially in the neonatal period. In this work, we studied the photochemistry of (Z)-isovinylneoxanthobilirubic acid methyl ester, a dipyrrinone subunit of BR, by steady-state absorption, femtosecond transient absorption, and stimulated Raman spectroscopies. Both the (Z)- and (E)-configurational isomers of isovinylneoxanthobilirubic acid undergo wavelength-dependent and reversible photoisomerization. The isomerization from the excited singlet state is ultrafast (the lifetimes of (Z)- and (E)- isomers were found to be ∼0.9 and 0.1 ps, respectively), and its efficiencies increase with increased photon energy. In addition, we studied sensitized photooxidation of the dipyrrinone subunit by singlet oxygen that leads to the formation of propentdyopents.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10303 - Particles and field physics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Organic Chemistry
ISSN
0022-3263
e-ISSN
1520-6904
Volume of the periodical
87
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
3089-3103
UT code for WoS article
000773458100083
EID of the result in the Scopus database
2-s2.0-85124902544