Structurally unique salts of cyamemazine and their pharmaceutical implications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F23%3A00570385" target="_blank" >RIV/68378271:_____/23:00570385 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/23:43926492
Result on the web
<a href="https://doi.org/10.1021/acs.cgd.2c00847" target="_blank" >https://doi.org/10.1021/acs.cgd.2c00847</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.cgd.2c00847" target="_blank" >10.1021/acs.cgd.2c00847</a>

Result language
angličtina
Original language name
Structurally unique salts of cyamemazine and their pharmaceutical implications
Original language description
The aim of this study was to prepare new crystalline salts of cyamemazine, an antipsychotic drug, with dicarboxylic acids, and compare their thermal stabilities, dissolution properties, and structural features. Among the eight acids investigated, we report novel salts with four acids, namely, L-malic, malonic, succinic, and fumaric acids. The study was extended to include the already known maleate and marketed L-tartrate salts as well. To the best of our knowledge, this is the first-ever study of the solid-state landscape of cyamemazine and report of its crystal structure.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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