Nanocomposite hydrogels from nanodiamonds and a self-assembling tripeptide
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F24%3A00603139" target="_blank" >RIV/68378271:_____/24:00603139 - isvavai.cz</a>
Result on the web
<a href="https://hdl.handle.net/11104/0361429" target="_blank" >https://hdl.handle.net/11104/0361429</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chem.202402961" target="_blank" >10.1002/chem.202402961</a>
Alternative languages
Result language
angličtina
Original language name
Nanocomposite hydrogels from nanodiamonds and a self-assembling tripeptide
Original language description
We report the successful assembly of a tripeptide in the presence of nanodiamonds (NDs) into nanocomposite hydrogels. While the presence of NDs does not hinder peptide selfassembly and gelation kinetics are not affected, NDs improve the viscoelastic properties and significantly increase the elastic moduli of the peptide hydrogels. Increased resistance of the gels against applied stress can also be attained depending on the amount of NDs loaded in the nanocomposite. Raman micro-spectroscopy and TEM confirmed the presence of NDs on the surface, and not in the interior, of peptide nanofibers. Peptide-ND non-covalent interactions are also probed by Raman and Fourier-transformed infrared spectroscopies. Overall, this work enables the embedding of NDs into nanocomposite hydrogels formed through the self-assembly of a simple tripeptide at physiological pH, and it provides key insights to open the way for their future applications in biomaterials, for instance exploiting their luminescence and near-infrared responsiveness.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/GA23-04876S" target="_blank" >GA23-04876S: Nanodiamonds as selective protein traps to regulate disorders caused by aberrant FGF2 signaling</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry - A European Journal
ISSN
0947-6539
e-ISSN
1521-3765
Volume of the periodical
30
Issue of the periodical within the volume
70
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
e202402961
UT code for WoS article
001357342800001
EID of the result in the Scopus database
2-s2.0-85208252231