Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F24%3A00604790" target="_blank" >RIV/68378271:_____/24:00604790 - isvavai.cz</a>
Result on the web
<a href="https://hdl.handle.net/11104/0362296" target="_blank" >https://hdl.handle.net/11104/0362296</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mtbio.2023.100932" target="_blank" >10.1016/j.mtbio.2023.100932</a>
Alternative languages
Result language
angličtina
Original language name
Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms
Original language description
Zinc (Zn)-based biodegradable metals (BMs) have emerged as promising bioactive materials because of their exceptional biocompatibility, appropriate mechanical properties, and controllable biodegradation. This review summarizes the state of the art in terms of Zn-based metals for bone repair and regeneration, focusing on bridging the gap between biological mechanism and required bioactivity. The molecular mechanism underlying the release of Zn ions from Zn-based BMs in the improvement of bone repair and regeneration is elucidated. By integrating clinical considerations and the specific bioactivity required for implant materials, this review summarizes the current research status of Zn-based internal fixation materials for promoting fracture healing, Zn-based scaffolds for regenerating critical-size bone defects, and Zn-based barrier membranes for reconstituting alveolar bone defects.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20501 - Materials engineering
Result continuities
Project
<a href="/en/project/GA23-05592S" target="_blank" >GA23-05592S: Influence of surface modifications on the functionality of zinc-based absorbable materials for applications in bone reconstructions</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials Today Bio
ISSN
2590-0064
e-ISSN
2590-0064
Volume of the periodical
25
Issue of the periodical within the volume
April
Country of publishing house
GB - UNITED KINGDOM
Number of pages
22
Pages from-to
100932
UT code for WoS article
001163177500001
EID of the result in the Scopus database
2-s2.0-85182516691