Surface chemical and electronic properties of functionalized Fe3O4 nanoparticles influencing their cytotoxicity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F25%3A00619411" target="_blank" >RIV/68378271:_____/25:00619411 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.apsusc.2024.161873" target="_blank" >https://doi.org/10.1016/j.apsusc.2024.161873</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apsusc.2024.161873" target="_blank" >10.1016/j.apsusc.2024.161873</a>
Alternative languages
Result language
angličtina
Original language name
Surface chemical and electronic properties of functionalized Fe3O4 nanoparticles influencing their cytotoxicity
Original language description
Physico-chemical, electronic and magnetic properties of bare Fe3O4 nanoparticles (NPs) and functionalized NPs (f-NPs) with doxorubicin, tannic acid, curcumin, polyethylene glycol and their mixtures were determined using DLS, XRD, XPS and AES. The cytotoxicity of bare and f-NPs for various cell lines such as normal HEK-293 and cancer HeLa, MDA-MB-231, and MCF-7 was studied by MTT assay. Bare and f-NPs exhibited different cytotoxicity dependent on molecules bonding at the surface. Cytotoxicity increases with decreasing hydrodynamic diameter and increasing Zeta-potential, increasing content of lattice and adsorbed O2-, carboxyl groups and C vacancies, NH4+ groups, decreasing overlayer thickness, electron charge transfer to oxygen and more nucleophilic character of electron rich surface oxygen.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Surface Science
ISSN
0169-4332
e-ISSN
1873-5584
Volume of the periodical
684
Issue of the periodical within the volume
Mar
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
14
Pages from-to
161873
UT code for WoS article
001406678800001
EID of the result in the Scopus database
2-s2.0-85210542253