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Ambient Particulate Air Pollution and Daily Mortality in 652 Cities

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378289%3A_____%2F19%3A00508320" target="_blank" >RIV/68378289:_____/19:00508320 - isvavai.cz</a>

  • Alternative codes found

    RIV/60460709:41330/19:79734

  • Result on the web

    <a href="https://www.nejm.org/doi/pdf/10.1056/NEJMoa1817364?articleTools=true" target="_blank" >https://www.nejm.org/doi/pdf/10.1056/NEJMoa1817364?articleTools=true</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1056/NEJMoa1817364" target="_blank" >10.1056/NEJMoa1817364</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ambient Particulate Air Pollution and Daily Mortality in 652 Cities

  • Original language description

    BackgroundThe systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias.nMethodsWe evaluated the associations of inhalable particulate matter (PM) with an aerodynamic diameter of 10 mu m or less (PM10) and fine PM with an aerodynamic diameter of 2.5 mu m or less (PM2.5) with daily all-cause, cardiovascular, and respiratory mortality across multiple countries or regions. Daily data on mortality and air pollution were collected from 652 cities in 24 countries or regions. We used overdispersed generalized additive models with random-effects meta-analysis to investigate the associations. Two-pollutant models were fitted to test the robustness of the associations. Concentration-response curves from each city were pooled to allow global estimates to be derived.nResultsOn average, an increase of 10 mu g per cubic meter in the 2-day moving average of PM10 concentration, which represents the average over the current and previous day, was associated with increases of 0.44% (95% confidence interval [CI], 0.39 to 0.50) in daily all-cause mortality, 0.36% (95% CI, 0.30 to 0.43) in daily cardiovascular mortality, and 0.47% (95% CI, 0.35 to 0.58) in daily respiratory mortality. The corresponding increases in daily mortality for the same change in PM2.5 concentration were 0.68% (95% CI, 0.59 to 0.77), 0.55% (95% CI, 0.45 to 0.66), and 0.74% (95% CI, 0.53 to 0.95). These associations remained significant after adjustment for gaseous pollutants. Associations were stronger in locations with lower annual mean PM concentrations and higher annual mean temperatures. The pooled concentration-response curves showed a consistent increase in daily mortality with increasing PM concentration, with steeper slopes at lower PM concentrations.nConclusionsOur data show independent associations between short-term exposure to PM10 and PM2.5 and daily all-cause, cardiovascular, and respiratory mortality in more than 600 cities across the globe. These data reinforce the evidence of a link between mortality and PM concentration established in regional and local studies. (Funded by the National Natural Science Foundation of China and others.)nModeling of the associations between mortality and air pollution data from 652 cities, mostly in the northern hemisphere, showed that concentrations of inhalable and fine particulate matter were associated with daily all-cause, cardiovascular, and respiratory mortality. An interactive map allows the reader to explore the geographic distribution of PM, and a Quick Take summarizes the findings in a short video.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10510 - Climatic research

Result continuities

  • Project

    <a href="/en/project/GA18-22125S" target="_blank" >GA18-22125S: Modelling weather-to-human health links</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    New England Journal of Medicine

  • ISSN

    0028-4793

  • e-ISSN

  • Volume of the periodical

    381

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    705-715

  • UT code for WoS article

    000483203400006

  • EID of the result in the Scopus database

    2-s2.0-85071318200