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Characterization of sodium alginate hydrogels reinforced with nanoparticles of hydroxyapatite for biomedical applications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378297%3A_____%2F21%3A00545224" target="_blank" >RIV/68378297:_____/21:00545224 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.3390/polym13172927" target="_blank" >https://doi.org/10.3390/polym13172927</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/polym13172927" target="_blank" >10.3390/polym13172927</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of sodium alginate hydrogels reinforced with nanoparticles of hydroxyapatite for biomedical applications

  • Original language description

    In recent years, researchers working in biomedical science and technology have investigated alternatives for enhancing the mechanical properties of biomedical materials. In this work, sodium alginate (SA) hydrogel-reinforced nanoparticles (NPs) of hydroxyapatite (HA) were prepared to enhance the mechanical properties of this polymer. Compression tests showed an increase of 354.54% in ultimate compressive strength (UCS), and 154.36% in Young’s modulus with the addition of these NPs compared with pure SA. Thermogravimetric analysis (TGA) revealed that the amount of residual water is not negligible and covered a range from 20 to 35 wt%, and the decomposition degree of the alginate depends on the hydroxyapatite content, possibly due to the displacement of sodium ions by the hydroxyapatite and not by calcium chloride. Further, there is an important effect possibly due to the existence of an interaction of hydrogen bonds between the hydroxyl of the alginate and the oxygen atoms of the hydroxyapatite, so signals appear upfield in nuclear magnetic resonance (NMR) data. An increase in the accumulation of HA particles was observed with the use of X-ray microtomography, in which the quantified volume of particles per reconstructed volume corresponded accordingly to the increase in the mechanical properties of the hydrogel.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20501 - Materials engineering

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000766" target="_blank" >EF16_019/0000766: Engineering applications of microworld physics</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Polymers

  • ISSN

    2073-4360

  • e-ISSN

    2073-4360

  • Volume of the periodical

    13

  • Issue of the periodical within the volume

    17

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    16

  • Pages from-to

    2927

  • UT code for WoS article

    000694328600001

  • EID of the result in the Scopus database

    2-s2.0-85114113327