Surface modification of cyclic olefin copolymers for osteochondral defect repair can increase pro-destructive potential of human chondrocytes in vitro

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21110%2F10%3A00172186" target="_blank" >RIV/68407700:21110/10:00172186 - isvavai.cz</a>

Alternative codes found

RIV/61388955:_____/10:00343392 RIV/61389013:_____/10:00343392 RIV/00023728:_____/10:#0000178 RIV/00216208:11110/10:6344 and 2 more

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Surface modification of cyclic olefin copolymers for osteochondral defect repair can increase pro-destructive potential of human chondrocytes in vitro

Original language description

Materials on the basis of cycloolefin copolymers (COC) are suitable for subchondral defect repairs. The objective of this study was to evaluate the influence of surface modification of COC and COC/LLDP blends on the viability and gene expression of chondrocytes. COC copolymers and their blends may represent suitable materials for tissue engineering, however, their modification followed by collagen type II application may, at least under in vitro conditions, reduce the viability of chondrocytes and induce their pro-destructive behavior.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/GA106%2F06%2F0761" target="_blank" >GA106/06/0761: Hybrid Biocomposite of a New Generation</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

59

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

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UT code for WoS article

000278016200012

EID of the result in the Scopus database

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