Replacement of Local Osteochondral Defects as Hybrid Biocomposite

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21110%2F11%3A00189924" target="_blank" >RIV/68407700:21110/11:00189924 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Replacement of Local Osteochondral Defects as Hybrid Biocomposite
Original language description
Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytes and many others (with more or less successfully). Provision of a long-term functional stability of inanimate implants in live surroundings is a complex and quite uneasy task. The development of replacements for a human subchondral bone and articular cartilage follows the path of a proposal and investigation of such materials whose mechanicalproperties are very similar to the biomechanical properties of a bone/cartilage tissue and whose biophysical and biochemical interactions do not lead to any disorders. The biophysical and biochemical fixation of replacements and/or scaffolds to the tissue depends dominantly: (a) on the biomechanical properties and biochemical environments of the implants and the tissue; (b) on the stress-strain distributions in the tissue and the replacement, (c) on the organization and stability of col
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FI - Traumatology and orthopaedics
OECD FORD branch
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Project
<a href="/en/project/GA106%2F06%2F0761" target="_blank" >GA106/06/0761: Hybrid Biocomposite of a New Generation</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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