Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F06%3A02126294" target="_blank" >RIV/68407700:21220/06:02126294 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Adhesion, Gowth and Differentiation Markers in Human Osteoblast-like Cells Cultured on Surface-modified Metallic Materials Designed for Bone Implants
Original language description
A several metallic materials with different surface treatments (machined pure Ti and Ti6Al4V, polished Ti and Ti6Al4V, and Ti5Al2.5Fe treated by electroerosion and plasma-sprayed with Ti) were seeded with human osteoblast-like cells MG 63. After one day,the highest cell numbers were obtained on the samples of medium surface roughness (T and TS; Ra 0.630.30 um and 0.890.57 um, respectively). From day 1 to 4, the cell proliferation was the quickest on the samples with the lowest surface roughness (TL and TSL; Ra 0.170.13 for both materials). The cells on TL also contained the highest concentration of integrin adhesion molecules with alpha V chain, i.e. receptors for vitronectin and fibronectin. On day 8 after seeding, the cells on all metallic samples and polystyrene reached similar population densities.
Czech name
Není k dispozici
Czech description
Není k dispozici

Project
<a href="/en/project/GA101%2F06%2F0226" target="_blank" >GA101/06/0226: Surface-modified carbon composites as potential implants into human body</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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