Biomechanics of nanoparticles self - assembly in lipid bilayer

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00224598" target="_blank" >RIV/68407700:21220/14:00224598 - isvavai.cz</a>

Result on the web

<a href="http://www.zcu.cz/pracoviste/vyd/online/Humanic_web.pdf" target="_blank" >http://www.zcu.cz/pracoviste/vyd/online/Humanic_web.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Biomechanics of nanoparticles self - assembly in lipid bilayer

Original language description

Nanoparticles aggregation in lipid bilayer depends on the method of preparation: forming distributed monolayer if prepared by extrusion process or forming hybrid vesicles with nanoparticles segregated into hemispherical domains if prepared by dialysis. The aim of the study was to explain two forms of nanoparticles configuration by assuming changes in biomembrane bending and stretching energy. Monte Carlo simulation of membrane mechanics shows that an energetical barrier exists between condensed and distributed configuration of membrane particles. We propose that two distinct forms of nanoparticles configuration corresponds to two energetically stable states.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

EI - Biotechnology and bionics

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů