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Collagen in bone tissue regeneration: Focusing on the mechanical and structural constraints

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F20%3A00362120" target="_blank" >RIV/68407700:21220/20:00362120 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Collagen in bone tissue regeneration: Focusing on the mechanical and structural constraints

  • Original language description

    This study demonstrates the effect of various processing conditions on the mechanical, structural and utility characteristics of collagen materials to be used for bone tissue regeneration purposes in both the microstructured and nanostructured forms. The first part presents the effective cross-linking conditions and composition of collagen microstructured composites, focusing on the collagen content and their final characteristics such as mechanical properties, internal structure and porosity in both the dry and hydrated states. The second part presents an assessment of the effective processing and cross-linking conditions of nanostructured electrospun collagen with respect to its mechanical and structural properties and the preservation of the native structure of the collagen. The third part presents the development of a biodegradable nanostructured electrospun composite layer for the treatment of implant-associated infections and improvements with respect to the rate of osseointegration.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    20302 - Applied mechanics

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů