NONLINEAR CELL DEFORMATION MODEL

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F23%3A00369524" target="_blank" >RIV/68407700:21220/23:00369524 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/23:00369524
Result on the web
<a href="https://doi.org/10.2478/scjme-2023-0026" target="_blank" >https://doi.org/10.2478/scjme-2023-0026</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/scjme-2023-0026" target="_blank" >10.2478/scjme-2023-0026</a>

Result language
angličtina
Original language name
NONLINEAR CELL DEFORMATION MODEL
Original language description
Cytoskeletal mechanics is a field that heavily relies on mathematical models to interpret experimental data related to forces and deformations. In this paper, we present a novel mathematical model designed specifically for analysing the mechanical properties of liposomes, which serve as model systems for studying biological membranes. Our model takes into account various factors such as stretching, bending, and contact adhesion during atomic force microscopy (AFM) indentation using a spherical tip. By applying our model to liposomes, we demonstrate that these structures exhibit nonlinear behaviour characterized by low stiffness at small deformations. Furthermore, we find that the mechanical response of liposomes is influenced by their size. Additionally, we observe that the presence of adhesion energy contributes to the generation of negative tip forces upon initial contact.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
20301 - Mechanical engineering

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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