Changes in Nasal Anatomy and Airflow After Endoscopic Resection of Pituitary Adenomas Using Computational Fluid Dynamics: A Pilot Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F25%3A00384237" target="_blank" >RIV/68407700:21220/25:00384237 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10507403

Result on the web

<a href="https://doi.org/10.7759/cureus.85568" target="_blank" >https://doi.org/10.7759/cureus.85568</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.7759/cureus.85568" target="_blank" >10.7759/cureus.85568</a>

Result language

angličtina

Original language name

Changes in Nasal Anatomy and Airflow After Endoscopic Resection of Pituitary Adenomas Using Computational Fluid Dynamics: A Pilot Study

Original language description

Purpose: Pituitary adenoma, a relatively common intracranial tumor, is often treated surgically through the nasal cavity, which alters its anatomy. This study aims to determine the severity of these changes in airflow and flow distribution within the nasal cavity, focusing on the anterior nasal region's role in airflow redistribution. Computational fluid dynamics (CFD) was employed to analyze these changes before and after surgery. Methods: Data from four patients of the Department of Neurosurgery and Neuro-oncology of the Military University Hospital, Prague, were analyzed using CFD simulations in Ansys Fluent 2021 R1. Computed tomography (CT) scans were used to model the nasal cavities pre- and post-surgery, creating polyhedral meshes of 1.8 million cells before surgery and 2.2 million cells after surgery. The k-ε turbulent model was applied to compute flow fields, providing consistent results across patients. Results: The surgery increased the nasal cavity volume, primarily due to the endonasal transsphenoidal approach. Cross-sectional areas, particularly in the middle nasal meatus, were enlarged, reducing airflow velocity without altering total volume flow. Most airflow was redistributed through the middle nasal meatus, while flow in peripheral regions decreased. The anterior part of the nasal cavity was identified as having the most significant influence on airflow redistribution. Conclusion: Surgery impacts nasal anatomy and airflow dynamics significantly, particularly in the anterior part of the nasal cavity. These findings emphasize the need for surgical precision to minimize unintended shifts in airflow patterns. Further studies are recommended to validate these observations.

Czech name

—

Czech description

—

Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

—

OECD FORD branch

20302 - Applied mechanics

Project

<a href="/en/project/NW24-08-00324" target="_blank" >NW24-08-00324: Morphological and functional analysis of pituitary adenomas: structure prediction and postoperative changes in nasal airflow and olfactory function</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cureus: Journal of Medical Science

ISSN

2168-8184

e-ISSN

2168-8184

Volume of the periodical

17

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

—

UT code for WoS article

—

EID of the result in the Scopus database

—