Searching for Important Amino Acids in DNA-binding Proteins for Histogram Methods
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F11%3A00181845" target="_blank" >RIV/68407700:21230/11:00181845 - isvavai.cz</a>
Result on the web
<a href="http://www.cs.gsu.edu/isbra11/wp-content/uploads/2010/07/ISBRA2011ShortAbstracts.pdf" target="_blank" >http://www.cs.gsu.edu/isbra11/wp-content/uploads/2010/07/ISBRA2011ShortAbstracts.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Searching for Important Amino Acids in DNA-binding Proteins for Histogram Methods
Original language description
We develop a method capable to identify important amino acids for histogram-based methods predicting DNA-binding propensity. This method can be used both for prediction from sequence information Tube Histograms) and prediction from structural information(Ball Histograms). We validate our method in prediction experiments using only proteins' primary structure, achieving favourable accuracies. Moreover, the histogram-based methods equipped with this new searching method also provide interpretable features involving distributions of amino acids.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JC - Computer hardware and software
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ME10047" target="_blank" >ME10047: Predictive Data Modeling for Effective Gene Therapy and Bone Marrow Transplantation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů