Abnormalities in Subcortical Motor Preparation in Patients with Idiopathic Cervical Dystonia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F11%3A00203682" target="_blank" >RIV/68407700:21230/11:00203682 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Abnormalities in Subcortical Motor Preparation in Patients with Idiopathic Cervical Dystonia
Original language description
In patients with cervical dystonia (CD), bradykinesia (slowness of movement) may co-exist with hyperkinesia. The pathophysiological mechanisms of bradykinesia in dystonia are incompletely understood. Our hypothesis is that, because of abnormalities in the integration of sensory inputs, patients with focal dystonia may not reach the adequate level of subcortical motor excitability that would lead to execution of the intended movement at the desired speed. Our aim therefore was to study preparation of subcortical motor circuits for task execution and neurophysiological measures of bradykinesia in patients with cervical dystonia (CD) by means of the so-called StartReact (SR) method. In this method, a startling auditory stimulus (SAS) is applied together with the imperative signal in a reaction time task paradigm. This causes faster movement execution of the prepared motor program.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JC - Computer hardware and software
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů