Targeting mitochondria for cancer treatment

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F12%3A00195443" target="_blank" >RIV/68407700:21230/12:00195443 - isvavai.cz</a>

Alternative codes found

RIV/67985882:_____/12:00387380 RIV/68407700:21460/12:00195443 RIV/00216208:11110/12:13567 RIV/00064165:_____/12:13567

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Targeting mitochondria for cancer treatment

Original language description

The paper is aimed to overview the published papers for analysis of the cancer treatment by restoration of normal physiological processes, in particular electromagnetic activity and apoptotic function of glycolytic phenotype cancer cells. Achievement ofthis target is based on estimation of the treatment based on bringing back normal mitochondrial function through inhibition of molecules (kinases) blocking the pyruvate pathway using dichloroacetate (DCA) or drugs with similar properties. This method issupported by considerable in vitro and in vivo experience by DCA treatment even in humans. Opening pyruvate pathway restores the proton space charge layer, the strong static electric field around mitochondria, ordering of water, and induction of strong non-linearity of microtubule electrically polar oscillations. Normal level of excitation of oscillations dependent on energy liberated from mitochondria and low damping keeps running physical processes regulated by electromagnetic field. D

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EUROPEAN JOURNAL OF ONCOLOGY

ISSN

1128-6598

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

1

Country of publishing house

IT - ITALY

Number of pages

14

Pages from-to

23-36

UT code for WoS article

000308133300003

EID of the result in the Scopus database

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