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Perioperative tight glucose control reduces postoperative adverse events in non-diabetic cardiac surgery patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F15%3A00233650" target="_blank" >RIV/68407700:21230/15:00233650 - isvavai.cz</a>

  • Result on the web

    <a href="http://press.endocrine.org/doi/abs/10.1210/jc.2015-1959" target="_blank" >http://press.endocrine.org/doi/abs/10.1210/jc.2015-1959</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1210/jc.2015-1959" target="_blank" >10.1210/jc.2015-1959</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Perioperative tight glucose control reduces postoperative adverse events in non-diabetic cardiac surgery patients

  • Original language description

    Context: Tight glucose control (TGC) reduces morbidity and mortality in patients undergoing elective cardiac surgery, but only limited data about its optimal timing are available to date. Objective: To compare the effects of perioperative (PERI) versus postoperative (POST) initiation of TGC on postoperative adverse events in cardiac surgery patients. Design: Single center, single-blind, parallel-group, randomized controlled trial. Settings: Academic tertiary hospital. Participants: 2383 hemodynamicallystable patients undergoing major cardiac surgery with expected postoperative ICU treatment for at least 2 consecutive days. Intervention: Perioperatively or postoperatively initiated intensive insulin therapy with target glucose range 4.4?6.1 mmol/l. Main Outcome Measures: Adverse events from any cause during postoperative hospital stay. Results: In the whole cohort, perioperatively initiated TGC markedly reduced the number of postoperative complications (23.2 vs. 34.1%, 95% CI 0.60?0.78

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    JC - Computer hardware and software

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    The Journal of Clinical Endocrinology & Metabolism

  • ISSN

    1945-7197

  • e-ISSN

  • Volume of the periodical

    Volume 100

  • Issue of the periodical within the volume

    Issue 8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    3081-3089

  • UT code for WoS article

  • EID of the result in the Scopus database