Perioperative tight glucose control reduces postoperative adverse events in non-diabetic cardiac surgery patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F15%3A00233650" target="_blank" >RIV/68407700:21230/15:00233650 - isvavai.cz</a>
Result on the web
<a href="http://press.endocrine.org/doi/abs/10.1210/jc.2015-1959" target="_blank" >http://press.endocrine.org/doi/abs/10.1210/jc.2015-1959</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1210/jc.2015-1959" target="_blank" >10.1210/jc.2015-1959</a>
Alternative languages
Result language
angličtina
Original language name
Perioperative tight glucose control reduces postoperative adverse events in non-diabetic cardiac surgery patients
Original language description
Context: Tight glucose control (TGC) reduces morbidity and mortality in patients undergoing elective cardiac surgery, but only limited data about its optimal timing are available to date. Objective: To compare the effects of perioperative (PERI) versus postoperative (POST) initiation of TGC on postoperative adverse events in cardiac surgery patients. Design: Single center, single-blind, parallel-group, randomized controlled trial. Settings: Academic tertiary hospital. Participants: 2383 hemodynamicallystable patients undergoing major cardiac surgery with expected postoperative ICU treatment for at least 2 consecutive days. Intervention: Perioperatively or postoperatively initiated intensive insulin therapy with target glucose range 4.4?6.1 mmol/l. Main Outcome Measures: Adverse events from any cause during postoperative hospital stay. Results: In the whole cohort, perioperatively initiated TGC markedly reduced the number of postoperative complications (23.2 vs. 34.1%, 95% CI 0.60?0.78
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JC - Computer hardware and software
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Journal of Clinical Endocrinology & Metabolism
ISSN
1945-7197
e-ISSN
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Volume of the periodical
Volume 100
Issue of the periodical within the volume
Issue 8
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
3081-3089
UT code for WoS article
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EID of the result in the Scopus database
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