Emotional valence and arousal gradient along the anterior-posterior axis within the subthalamic nucleus in Parkinson's disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F16%3A00307361" target="_blank" >RIV/68407700:21230/16:00307361 - isvavai.cz</a>
Result on the web
<a href="http://www.clinph-journal.com/article/S1388-2457(16)30293-0/abstract" target="_blank" >http://www.clinph-journal.com/article/S1388-2457(16)30293-0/abstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clinph.2016.05.237" target="_blank" >10.1016/j.clinph.2016.05.237</a>
Alternative languages
Result language
angličtina
Original language name
Emotional valence and arousal gradient along the anterior-posterior axis within the subthalamic nucleus in Parkinson's disease
Original language description
Changes in emotional processes have been reported after deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson’s disease (PD). The STN DBS increased activity of the aversive motivational system: the fearful stimuli were experienced as more salient with the DBS switched on. The STN is organized into a dorsolateral motor, a central associative, and a ventromedial limbic territories and clinical effects of STN DBS seem to depend on the position of the active electrode contact within the STN in a manner that reflects the functional organization and connectivity of the STN. Considering the functional organization of the STN, we aimed to analyze the relationship between changes in subjective emotional experience to pictures presenting fearful stimuli and the active electrode contact position within the STN. Our results confirm previous observations STN DBS affects emotional processing related to aversive stimuli. They further suggest emotional valence and arousal are processed separately at this subcortical level and their representations are organized along the anterior–posterior axis in the STN.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JD - Use of computers, robotics and its application
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA16-13323S" target="_blank" >GA16-13323S: MIcro and MAcro Connectomics of the Subthalamic nucleus in humans: impact of neuromodulation and dopamine depletion</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů