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Feature subset selection and classification of intracardiac electrograms during atrial fibrillation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F17%3A00312281" target="_blank" >RIV/68407700:21230/17:00312281 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21730/17:00312281

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S1746809417301088" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1746809417301088</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bspc.2017.06.005" target="_blank" >10.1016/j.bspc.2017.06.005</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Feature subset selection and classification of intracardiac electrograms during atrial fibrillation

  • Original language description

    Several approaches have been adopted for the identification of arrhythmogenic sources maintaining atrial fibrillation (AF). In this paper, we propose a classifier that discriminates between four classes of atrial electrogram (EGM). We delved into the relation between levels of fractionation in EGM signals and the fibrillation substrates in simulated episodes of chronic AF. Several feature extraction methods were used to calculate 92 features from 429 real EGM records acquired during radiofrequency ablation of chronic AF. We selected the optimal subset of features by using a genetic algorithm, followed by K-nearest neighbors (K-NN) classification into four levels of fractionation. Sensitivity of 0.90 and specificity of 0.97 were achieved. Subsequently, the results of the classification were extrapolated to signals of a 3D human atria model and a 2D model of atrial tissue. The 3D model simulated an episode of AF maintained by a rotor in the posterior wall of the left atrium and the 2D model simulated an AF episode with one stable rotor. We used the K-NN classifier trained on a given set of real EGM signals to detect a specific class of signals presenting the highest level of fractionation located near the rotor's vortex. This method needs to be tested on real clinical data to provide evidence that it can support ablation therapy procedures.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Result continuities

  • Project

    <a href="/en/project/GPP103%2F11%2FP106" target="_blank" >GPP103/11/P106: Integration of digital signal processing and artificial intelligence methods for intracardial signal complexity evaluation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Signal Processing and Control

  • ISSN

    1746-8094

  • e-ISSN

    1746-8108

  • Volume of the periodical

    38

  • Issue of the periodical within the volume

    September

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    182-190

  • UT code for WoS article

    000409290400020

  • EID of the result in the Scopus database

    2-s2.0-85021174952