Validation of cepstral peak prominence in assessing early voice changes of Parkinson’s disease: effect of speaking task and ambient noise.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F21%3A00353824" target="_blank" >RIV/68407700:21230/21:00353824 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/21:10436627
Result on the web
<a href="https://doi.org/10.1121/10.0009063" target="_blank" >https://doi.org/10.1121/10.0009063</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1121/10.0009063" target="_blank" >10.1121/10.0009063</a>
Alternative languages
Result language
angličtina
Original language name
Validation of cepstral peak prominence in assessing early voice changes of Parkinson’s disease: effect of speaking task and ambient noise.
Original language description
Although cepstral peak prominence (CPP) and its smooth variant (CPPS) are considered robust acoustic measures for the evaluation of dysphonia, whether they are sensitive to capture early voice changes in Parkinson’s disease (PD) has not yet been explored. This study aimed to investigate voice changes via CPP measures in idiopathic rapid eye movement sleep disorder behaviour (iRBD), a special case of prodromal neurodegeneration, and in both newly diagnosed, and advanced-stage PD patients using different speaking tasks across noise-free and noisy environments. The sustained vowel phonation, the reading of passages and the monologues of 60 early-stage untreated PD, 30 advanced-stage PD, 60 iRBD, and 60 healthy control (HC) participants were evaluated. We found significant differences between both PD groups and the controls in sustained phonation via CPP (p < 0.05) and CPPS (p < 0.01) and in monologue via CPP (p < 0.01), although neither CPP nor CPPS measures were sufficiently sensitive to capture possible prodromal dysphonia in iRBD. The quality of both CPP and CPPS measures was influenced substantially by the addition of ambient noise. We anticipated that CPP measures might serve as a promising digital biomarker in assessing dysphonia from the early stages of PD.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Journal of the Acoustical Society of America
ISSN
0001-4966
e-ISSN
1520-8524
Volume of the periodical
150
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
4522-4533
UT code for WoS article
000739073700005
EID of the result in the Scopus database
2-s2.0-85122543986