Distinct patterns of interictal intracranial EEG in focal cortical dysplasia type I and II
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F23%3A00364919" target="_blank" >RIV/68407700:21230/23:00364919 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/23:10462217 RIV/00216208:11130/23:10462217
Result on the web
<a href="https://doi.org/10.1016/j.clinph.2023.03.360" target="_blank" >https://doi.org/10.1016/j.clinph.2023.03.360</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clinph.2023.03.360" target="_blank" >10.1016/j.clinph.2023.03.360</a>
Alternative languages
Result language
angličtina
Original language name
Distinct patterns of interictal intracranial EEG in focal cortical dysplasia type I and II
Original language description
Objective: Focal cortical dysplasia (FCD) is the most common malformation causing refractory focal epilepsy. Surgical removal of the entire dysplastic cortex is crucial for achieving a seizure-free outcome. Precise presurgical distinctions between FCD types by neuroimaging are difficult, mainly in patients with normal magnetic resonance imaging findings. However, the FCD type is important for planning the extent of surgical approach and counselling. Methods: This study included patients with focal drug-resistant epilepsy and definite histopathological FCD type I or II diagnoses who underwent intracranial electroencephalography (iEEG). We detected interictal epileptiform discharges (IEDs) and their recruitment into repetitive discharges (RDs) to compare electrophysiological patterns characterizing FCD types. Results: Patients with FCD type II had a significantly higher IED rate (p<0.005), a shorter inter-discharge interval within RD episodes (p<0.003), sleep influence on decreased RD periodicity (p<0.036), and longer RD episode duration (p<0.003) than patients with type I. A Bayesian classifier stratified FCD types with 82% accuracy. Conclusion: Temporal characteristics of IEDs and RDs reflect the histological findings of FCD subtypes and can differentiate FCD types I and II. Significance: Presurgical prediction of FCD type can help to plan a more tailored surgical approach in patients with normal magnetic resonance findings.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Neurophysiology
ISSN
1388-2457
e-ISSN
1872-8952
Volume of the periodical
151
Issue of the periodical within the volume
7
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
10-17
UT code for WoS article
000991291400001
EID of the result in the Scopus database
2-s2.0-85153800585