Feasible Simulation of Diseases Related to Bone Remodelling and of Their Treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F11%3A00185417" target="_blank" >RIV/68407700:21340/11:00185417 - isvavai.cz</a>
Alternative codes found
RIV/61388998:_____/11:00370475
Result on the web
<a href="http://www.intechopen.com/articles/show/title/feasible-simulation-of-diseases-related-to-bone-remodelling-and-of-their-treatment" target="_blank" >http://www.intechopen.com/articles/show/title/feasible-simulation-of-diseases-related-to-bone-remodelling-and-of-their-treatment</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Feasible Simulation of Diseases Related to Bone Remodelling and of Their Treatment
Original language description
In this chapter, a more detailed influences of various biochemical factors will be added into the bone remodelling model through the RANKL-RANK-OPG chain mediating the effects of majority of acting hormones, growth factors, and cytokines. Physical activity (dynamic loading) is very essential in bone adaptation process. The addition of control factors will enable to predict concrete effects of changes of serum levels of these control factors of bone remodelling such as PTH, NO. The possibility of including vitamin D and TGF-beta into the model is also being discussed. Several diseases and their possible treatment is simulated, e.g. influence of menopause, hyperparathyroidism, and disuse.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
FI - Traumatology and orthopaedics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA106%2F08%2F0557" target="_blank" >GA106/08/0557: Material properties of veins and their remodelling</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Theoretical Biomechanics
ISBN
978-953-307-851-9
Number of pages of the result
24
Pages from-to
187-210
Number of pages of the book
402
Publisher name
InTech
Place of publication
Rijeka
UT code for WoS chapter
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