Investigating stress shielding spanned by biomimetic polymer-composite vs. metallic hip stem: A computational study using mechano-biochemical model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F15%3A00228090" target="_blank" >RIV/68407700:21340/15:00228090 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jmbbm.2014.09.019" target="_blank" >http://dx.doi.org/10.1016/j.jmbbm.2014.09.019</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jmbbm.2014.09.019" target="_blank" >10.1016/j.jmbbm.2014.09.019</a>

Result language
angličtina
Original language name
Investigating stress shielding spanned by biomimetic polymer-composite vs. metallic hip stem: A computational study using mechano-biochemical model
Original language description
Periprosthetic bone loss in response to total hip arthroplasty is a serious complication compromising patient's life quality as it may cause the premature failure of the implant. Stress shielding as a result of an uneven load sharing between the hip implant and the bone is a key factor leading to bone density decrease. A number of composite hip implants have been designed so far to improve load sharing characteristics. However, they have rarely been investigated from the bone remodeling point of view topredict a long-term response. This is the first study that employed a mechano-biochemical model, which considers the coupling effect between mechanical loading and bone biochemistry, to investigate bone remodeling after composite hip implantation. In this study, periprosthetic bone remodeling in the presence of Carbon fiber polyamide 12 (CF/PA12), CoCrMo and Ti alloy implants was predicted and compared. Our findings revealed that the most significant periprosthetic bone loss in response
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FI - Traumatology and orthopaedics
OECD FORD branch
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
Journal of the Mechanical Behavior of Biomedical Materials
ISSN
1751-6161
e-ISSN
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Volume of the periodical
41
Issue of the periodical within the volume
Jan
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
12
Pages from-to
56-67
UT code for WoS article
000346217400006
EID of the result in the Scopus database
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